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CYP1B1-IN-4

CAS No. 2685779-55-7

CYP1B1-IN-4( —— )

Catalog No. M36490 CAS No. 2685779-55-7

CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	43	In Stock
5MG	31	In Stock
10MG	50	In Stock
25MG	102	In Stock
50MG	161	In Stock
100MG	239	In Stock
200MG	352	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CYP1B1-IN-4
Note

Research use only, not for human use.
Brief Description

CYP1B1-IN-4, a 2,4-diarylthiazole compound, exhibits selective inhibition of CYP1B1 (IC50=0.2 nM), demonstrating minimal cytotoxicity and high stability in human and rat liver microsomes .
Description

CYP1B1-IN-4 is a 2,4-diarylthiazole compound with selectively CYP1B1 inhibition (IC50=0.2 nM). CYP1B1-IN-4 has little cytotoxicity and high stability in both human and rat liver microsomes.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

P450
Recptor

P450
Research Area

——
Indication

——

Chemical Information

CAS Number

2685779-55-7
Formula Weight

322.38
Molecular Formula

C18H14N2O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (193.87 mM; Ultrasonic )
SMILES

O(C)C1=C(C2=NC(=CS2)C3=CC=C(C#N)C=C3)C=CC(OC)=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hachey AC, et al. Design of Cytochrome P450 1B1 Inhibitors via a Scaffold-Hopping Approach. J Med Chem. 2022 Dec 15. ?

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