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Myosin V-IN-1
CAS No. 1259177-59-7
Myosin V-IN-1( —— )
Catalog No. M36423 CAS No. 1259177-59-7
Myosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPase by selectively inhibiting the release of ADP from the actinoglobulin complex.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 677 | In Stock |
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| 5MG | 663 | In Stock |
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| 10MG | 943 | In Stock |
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| 25MG | 1397 | In Stock |
|
| 50MG | 1851 | In Stock |
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| 100MG | 2492 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMyosin V-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionMyosin V-IN-1 is a potent and selective inhibitor of Myosin V with a Ki value of 6 μM.Myosin V-IN-1 inhibits actin V and slows down actin-activated myosin V ATPase by selectively inhibiting the release of ADP from the actinoglobulin complex.
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DescriptionMyosin V-IN-1 (compound 8) is a potent and selective Myosin V inhibitor, with a Ki of 6 μM. Myosin V-IN-1 shows acute inhibition of myosin V. Myosin V-IN-1 slows the actin-activated myosin V ATPase by specifically inhibiting ADP release from the actomyosin complex.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMyosin
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RecptorMyosin
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Research Area——
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Indication——
Chemical Information
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CAS Number1259177-59-7
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Formula Weight538.62
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Molecular FormulaC29H26N6O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (185.66 mM; Ultrasonic )
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SMILESN(C=1N=C2C(C(=NN2)C3=CC=C(C=C3)N4CCOCC4)=CN1)C5=CC(CSC6=CC(C(O)=O)=CC=C6)=CC=C5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Maschi D, et al. Myosin V Regulates Spatial Localization of Different Forms of Neurotransmitter Release in Central Synapses. Front Synaptic Neurosci. 2021 Apr 15;13:650334. ?
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