ZIM

CAS No. 301298-87-3

ZIM( —— )

Catalog No. M36395 CAS No. 301298-87-3

ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 32 In Stock
10MG 35 In Stock
25MG 71 In Stock
50MG 116 In Stock
100MG 186 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ZIM
  • Note
    Research use only, not for human use.
  • Brief Description
    ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation.
  • Description
    ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    301298-87-3
  • Formula Weight
    349.38
  • Molecular Formula
    C20H19N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (143.11 mM; Ultrasonic (<60°C)
  • SMILES
    CN1N(C(=O)C(N2C(=O)C3C4CC(C=C4)C3C2=O)=C1C)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rodrigo Juliano Oliveira, et al. ZIM, a Norbornene Derived from 4-Aminoantipyrine, Induces DNA Damage and Cell Death but in Association Reduces the Effect of Commercial Chemotherapeutics. Chem Res Toxicol. 2022 Dec 22.??
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