ZEN-2759

CAS No. 1616400-50-0

ZEN-2759( —— )

Catalog No. M36339 CAS No. 1616400-50-0

ZEN-2759 is a potent BET small molecule inhibitor of BRD4 (BD1), BRD4 (BD2), and BRD4 (BD1BD2).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 86 In Stock
10MG 131 In Stock
25MG 220 In Stock
50MG 323 In Stock
100MG 451 In Stock
200MG 639 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    ZEN-2759
  • Note
    Research use only, not for human use.
  • Brief Description
    ZEN-2759 is a potent BET small molecule inhibitor of BRD4 (BD1), BRD4 (BD2), and BRD4 (BD1BD2).
  • Description
    ZEN-2759 is a potent BET (Bromodomain and Extra-Terminal Domain) inhibitor, with IC50 values of 0.23, 0.08 and 0.28 μM for BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2), respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Epigenetic Reader Domain
  • Recptor
    Epigenetic Reader Domain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1616400-50-0
  • Formula Weight
    280.32
  • Molecular Formula
    C17H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (356.74 mM; Ultrasonic )
  • SMILES
    CC=1C(C2=CN(CC3=CC=CC=C3)C(=O)C=C2)=C(C)ON1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211. ?
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