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PU-H71 HCl

CAS No. 2095432-24-7

PU-H71 HCl( —— )

Catalog No. M36291 CAS No. 2095432-24-7

PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.

Purity : >98% (HPLC)

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25MG	938	In Stock
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100MG	1702	In Stock
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500MG	3422	In Stock
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Biological Information

Product Name

PU-H71 HCl
Note

Research use only, not for human use.
Brief Description

PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.
Description

PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP | DNA/RNA Synthesis
Research Area

——
Indication

——

Chemical Information

CAS Number

2095432-24-7
Formula Weight

548.83
Molecular Formula

C18H22ClIN6O2S
Purity

>98% (HPLC)
Solubility

——
SMILES

Cl.IC=1C=C2OCOC2=CC1SC3=NC=4C(=NC=NC4N3CCCNC(C)C)N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

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