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BTB09089
CAS No. 245728-44-3
BTB09089( —— )
Catalog No. M36055 CAS No. 245728-44-3
BTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and macrophages.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 153 | In Stock |
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| 5MG | 120 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 343 | In Stock |
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| 50MG | 511 | In Stock |
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| 100MG | 734 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1516 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBTB09089
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NoteResearch use only, not for human use.
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Brief DescriptionBTB09089 (GPR65 agonist ) is a T cell death-associated gene 8 (TDAG8/GPR65)-specific agonist.BTB09089 induces TDAG8 expression and regulates cytokine production in T cells and macrophages.
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DescriptionBTB09089 is a T cell death-associated gene 8 (TDAG8/GPR65) specific agonist. BTB09089 increases TDAG8 expression and regulates the cytokine production of T cells and macrophages.
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In Vitro——
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In VivoAnimal Model:Adult male SD rats (270-280 g), middle cerebral artery occlusion (MCAO) model Dosage:5, 10 and 20 μM, 8 μL Administration:Intracerebroventricular injection, six hours prior to MCAO Result:Up-regulated TDAG8 and Bcl-2 expression and down-regulated cleaved caspase-3 expression, while the infarction volume was reduced, and neurological deficits were ameliorated 24 and 72 h after MCAO.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorGPR | DNA
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Research Area——
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Indication——
Chemical Information
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CAS Number245728-44-3
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Formula Weight387.31
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Molecular FormulaC14H12Cl2N4OS2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (258.19 mM; Ultrasonic (<80°C)
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SMILESCN1C2=C(SC(SCC3=C(Cl)C=C(Cl)C=C3)=N1)C(=O)N(C)N=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Onozawa Y, et al. Activation of T cell death-associated gene 8 regulates the cytokine production of T cells and macrophages in vitro. Eur J Pharmacol. 2012 May 15;683(1-3):325-31.?
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