ALDH2 modulator 1

CAS No. 1629615-99-1

ALDH2 modulator 1( —— )

Catalog No. M36013 CAS No. 1629615-99-1

ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 147 Get Quote
5MG 278 Get Quote
10MG 440 Get Quote
25MG 702 Get Quote
50MG 984 Get Quote
100MG 1287 Get Quote
500MG 2601 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ALDH2 modulator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    ALDH2 modulator 1 is a potent, orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
  • Description
    ALDH2 modulator 1 is a potent and orally active aldehyde dehydrogenase-2 (ALDH2) modulator. ALDH2 modulator 1 reduces blood alcohol levels in mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:8-9 weeks, 20-22 g, Male C57BL6 mice (treated with PO 5/kg of EtOH) Dosage:40, 60 mg/kg for p.o. or 10 mg/kg for i.v.Administration:P.o. or i.v.Result:Reduced blood alcohol levels in mice treated with PO 5 g/kg of EtOH.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    Dehydrogenase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1629615-99-1
  • Formula Weight
    364.8
  • Molecular Formula
    C18H18ClFN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(CC1CC1)C2=C(C(NCC3=CC(F)=C(OC)C=C3)=O)C(Cl)=CC=N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wenjin Yang, et al. Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof. WO2014160185A2.
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