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trans-isrib A17
CAS No. 1628478-15-8
trans-isrib A17( —— )
Catalog No. M35981 CAS No. 1628478-15-8
trans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 74 | In Stock |
|
| 5MG | 69 | In Stock |
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| 10MG | 103 | In Stock |
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| 25MG | 211 | In Stock |
|
| 50MG | 305 | In Stock |
|
| 100MG | 436 | In Stock |
|
| 200MG | 629 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nametrans-isrib A17
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NoteResearch use only, not for human use.
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Brief Descriptiontrans-isrib A17 (ISR-IN-1) is an potent inhibitor of the integrated stress response with EC50 of 0.6 nM.
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DescriptionISR-IN-1 (Compound 48) is an inhibitor of the integrated stress response (EC50: 0.6 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1628478-15-8
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Formula Weight487.32
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Molecular FormulaC22H22Cl2F2N2O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 12.5 mg/mL (25.65 mM; Ultrasonic )
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SMILESO(CC(N[C@H]1CC[C@H](NC(COC2=CC(F)=C(Cl)C=C2)=O)CC1)=O)C3=CC(F)=C(Cl)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. ?
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