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dCeMM1
CAS No. 118719-16-7
dCeMM1( —— )
Catalog No. M35978 CAS No. 118719-16-7
dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 61 | In Stock |
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| 10MG | 83 | In Stock |
|
| 25MG | 145 | In Stock |
|
| 50MG | 230 | In Stock |
|
| 100MG | 368 | In Stock |
|
| 200MG | 527 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamedCeMM1
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NoteResearch use only, not for human use.
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Brief DescriptiondCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.
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DescriptiondCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells.
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In VitroWestern Blot Analysis Cell Line:WT and UBE2Mmut KBM7 cells Concentration:10 μM Incubation Time:12, 16 h Result:Decreased the expression of RBM39 levels in WT KBM7 cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMolecular Glues
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Research Area——
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Indication——
Chemical Information
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CAS Number118719-16-7
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Formula Weight369.23
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Molecular FormulaC14H13BrN2O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (270.83 mM; Ultrasonic )
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SMILESCc1ccc(cc1)S(=O)(=O)NN=Cc1cc(Br)ccc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.
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