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dCeMM1

CAS No. 118719-16-7

dCeMM1( —— )

Catalog No. M35978 CAS No. 118719-16-7

dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 83 In Stock
25MG 145 In Stock
50MG 230 In Stock
100MG 368 In Stock
200MG 527 In Stock
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Biological Information

  • Product Name
    dCeMM1
  • Note
    Research use only, not for human use.
  • Brief Description
    dCeMM1, a RBM39 glue degrader, re-directs the activity of the CRL4DCAF15 ligase and decreases RBM39 expression levels in WT KBM7 cells.
  • Description
    dCeMM1 is a RBM39 glue degrader. dCeMM1 shows functions by re-directing the activity of the CRL4DCAF15 ligase. dCeMM1 decreases the expression of RBM39 levels in WT KBM7 cells.
  • In Vitro
    Western Blot Analysis Cell Line:WT and UBE2Mmut KBM7 cells Concentration:10 μM Incubation Time:12, 16 h Result:Decreased the expression of RBM39 levels in WT KBM7 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Molecular Glues
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    118719-16-7
  • Formula Weight
    369.23
  • Molecular Formula
    C14H13BrN2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (270.83 mM; Ultrasonic )
  • SMILES
    Cc1ccc(cc1)S(=O)(=O)NN=Cc1cc(Br)ccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mayor-Ruiz C, et al. Rational discovery of molecular glue degraders via scalable chemical profiling. Nat Chem Biol. 2020 Nov;16(11):1199-1207.
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