Cart
sales@molnova.com
ROCK-IN-5
CAS No. 692870-25-0
ROCK-IN-5( —— )
Catalog No. M35956 CAS No. 692870-25-0
ROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC, with potential applications in cardiac, proliferative, and neurodegenerative disease research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 36 | Get Quote |
|
| 25MG | 58 | Get Quote |
|
| 50MG | 84 | Get Quote |
|
| 100MG | 123 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameROCK-IN-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionROCK-IN-5 (compound I-B-37) is a potent inhibitor of protein kinases, including ROCK, ERK, GSK, and AGC, with potential applications in cardiac, proliferative, and neurodegenerative disease research.
-
DescriptionROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetROCK
-
RecptorROCK | ERK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number692870-25-0
-
Formula Weight347.79
-
Molecular FormulaC16H11ClFN3OS
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESFC1=C(CC(=O)NC2=NC(=CS2)C2=CC=NC=C2)C(Cl)=CC=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jingrong Cao, et al. Compositions useful as inhibitors of rock and other protein kinases. WO2004041813A1.
molnova catalog
related products
-
Verosudil
Verosudil (AR-12286) is a potent ROCK inhibitor (Ki=0.2 nM) that effectively lowers intraocular pressure (IOP) in animal models and human subjects.
-
Y-33075 dihydrochlor...
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).Y-33075 (Y-39983) is a potent inhibitor of ROCK(IC50 of 3.6 nM). Y-33075 also inhibits PKC and CaMKII more potently than Y-27632(IC50s of Y-27632 and Y-33075 for PKC are 9.0 μM and 0.42 μM, respectively), whereas the IC50s of Y-27632 and Y-33075 for CaMKII are 26 μM and 0.81 μM, respectively.
-
NSC 409012
NSC 409012 is an active compound.
