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H-1152 dihydrochloride
CAS No. 871543-07-6
H-1152 dihydrochloride( —— )
Catalog No. M34747 CAS No. 871543-07-6
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | Get Quote |
|
| 5MG | 138 | Get Quote |
|
| 10MG | 227 | Get Quote |
|
| 25MG | 425 | Get Quote |
|
| 50MG | 670 | Get Quote |
|
| 100MG | 888 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameH-1152 dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionH-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM.
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DescriptionH-1152 dihydrochloride is a membrane-permeable and selective ROCK inhibitor, with a Ki value of 1.6 nM, and an IC50 value of 12 nM for ROCK2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetROCK
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RecptorROCK
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Research Area——
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Indication——
Chemical Information
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CAS Number871543-07-6
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Formula Weight392.34
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Molecular FormulaC16H23Cl2N3O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 35.71 mg/mL (91.02 mM; Ultrasonic)DMSO : 10 mg/mL (25.49 mM; Ultrasonic (<60°C)
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SMILESCl.Cl.C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(C)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tamura M, et al. Development of specific Rho-kinase inhibitors and their clinical application. Biochim Biophys Acta. 2005 Dec 30;1754(1-2):245-52. Epub 2005 Sep 12.?
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