TP-16

CAS No. 2332972-26-4

TP-16( —— )

Catalog No. M35651 CAS No. 2332972-26-4

TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 702 Get Quote
5MG 1017 Get Quote
25MG 1960 Get Quote
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Biological Information

  • Product Name
    TP-16
  • Note
    Research use only, not for human use.
  • Brief Description
    TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
  • Description
    TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    Prostaglandin Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2332972-26-4
  • Formula Weight
    439.5
  • Molecular Formula
    C24H22FNO4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)(=O)C=2C3=C(SC2CC4=CC=C(F)C=C4)COCC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798. ?
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