TP-16( —— )

Catalog No. M35651 CAS No. 2332972-26-4

TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

TP-16
Note

Research use only, not for human use.
Brief Description

TP-16 is a novel potent and selective EP4 antagonist that blocks the function of IMCs and enhances cytotoxic T cell-mediated tumor elimination in vivo.
Description

TP-16 is a novel and selective EP4 antagonist with an IC50 of 2.1 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Prostaglandin Receptor
Recptor

Prostaglandin Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

2332972-26-4
Formula Weight

439.5
Molecular Formula

C24H22FNO4S
Purity

>98% (HPLC)
Solubility

——
SMILES

C(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)(=O)C=2C3=C(SC2CC4=CC=C(F)C=C4)COCC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lu W, et al. Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer. EMBO Mol Med. 2021 Jan 11;13(1):e12798. ?

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