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GW 627368X
CAS No. 439288-66-1
GW 627368X( GW627368X | GW 627368X | GW-627368X | GW627368 )
Catalog No. M14493 CAS No. 439288-66-1
GW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 75 | In Stock |
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| 25MG | 126 | In Stock |
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| 50MG | 210 | In Stock |
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| 100MG | 369 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGW 627368X
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NoteResearch use only, not for human use.
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Brief DescriptionGW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).
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DescriptionGW627368(GW627368X) is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM).
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In Vitro——
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In VivoAnimal Model:6-8 weeks Swiss albino mice Dosage:0 mg/kg, 5 mg/kg, 10 mg/kg, 15 mg/kg, 15 mg/kg Administration:Oral administration, every alternate day for 28 days Result:Displayed anti-tumor and anti-proliferative potential in sarcoma 180 bearing mice.
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SynonymsGW627368X | GW 627368X | GW-627368X | GW627368
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PathwayGPCR/G Protein
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TargetProstaglandin Receptor
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RecptorEP4
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number439288-66-1
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Formula Weight544.62
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Molecular FormulaC30H28N2O6S
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mg/mL
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SMILESO=C(NS(=O)(C1=CC=CC=C1)=O)CC2=CC=C(N(CC3=C4C(OCC)=C(C=CC=C5)C5=C3OCC)C4=O)C=C2
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Chemical Name2-(4-(4,9-diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl)-N-(phenylsulfonyl)acetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wilson RJ, et al. Br J Pharmacol. 2006 Jun; 148(3): 326-39.
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