FGFR2-IN-2( —— )

Catalog No. M35560 CAS No. 2677709-81-6

FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FGFR2-IN-2
Note

Research use only, not for human use.
Brief Description

FGFR2-IN-2 is a specific FGFR2 inhibitor that inhibits FGFR1, FGFR2, and FGFR3, and can be used in the study of cancer and cardiovascular disease.
Description

FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

FGFR
Recptor

FGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

2677709-81-6
Formula Weight

370.45
Molecular Formula

C23H22N4O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 62.5 mg/mL (168.71 mM; Ultrasonic (<60°C)
SMILES

Oc1ccc(cc1)-c1ccc2c(n[nH]c2c1)-c1ccc(cc1)N1CCNCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.?

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