hnps-PLA Inhibitor( hnps-PLA Inhibitor | MDK-8582 | MDK 8582 )

Catalog No. M17396 CAS No. 185298-58-2

Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	132	In Stock
2MG	70	In Stock
5MG	116	In Stock
10MG	202	In Stock
25MG	341	In Stock
50MG	498	In Stock
100MG	710	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

hnps-PLA Inhibitor
Note

Research use only, not for human use.
Brief Description

Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
Description

MDK-8582, also known as Hnps-PLA Inhibitor, is an nhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA). The best one inhibited hnps-PLA(2) and LTA(4)H-h with IC(50) values of 9.2 ± 0.5 μM and 2.4 ± 1.4 μM, respectively.
In Vitro

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In Vivo

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Synonyms

hnps-PLA Inhibitor | MDK-8582 | MDK 8582
Pathway

Angiogenesis
Target

FGFR
Recptor

LTA(4)H-h| hnsPLA2
Research Area

——
Indication

——

Chemical Information

CAS Number

185298-58-2
Formula Weight

379.42
Molecular Formula

C21H21N3O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(N)C(=O)c1c(CC)n(Cc2ccccc2)c2c1c(OCC(=O)N)ccc2
Chemical Name

2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Meng H, Liu Y, Zhai Y, Lai L. Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase. Eur J Med Chem. 2013 Jan;59:160-7

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