Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Antifungal - APX2039

APX2039

CAS No. 2342606-49-7

APX2039( —— )

Catalog No. M35548 CAS No. 2342606-49-7

APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 303 In Stock
5MG 275 In Stock
10MG 411 In Stock
25MG 725 In Stock
50MG 1014 In Stock
100MG 1395 In Stock
200MG 1841 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    APX2039
  • Note
    Research use only, not for human use.
  • Brief Description
    APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activity against C. neoformans and C. gattii.
  • Description
    APX2039 is an orally active and potent inhibitor of the fungal Gwt1 enzyme. APX2039 has extremely potent anticryptococcal activity against C. neoformans and C. gattii. APX2039 blocks the localization of GPI (glycosylphosphatidyl inositol)-anchored cell wall mannoproteins. APX2039 can be used for Cryptococcal meningitis (CM) research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifungal
  • Recptor
    Antifungal
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2342606-49-7
  • Formula Weight
    362.36
  • Molecular Formula
    C20H15FN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (275.97 mM; Ultrasonic )
  • SMILES
    Nc1ncccc1-c1cc(Cc2ccc(Oc3cccc(F)n3)cc2)no1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Karen J Shaw, et al. 168. Efficacy of the Novel gwt1 Inhibitor APX2039 in a Rabbit Model of cryptococcus Meningitis. Open Forum Infect Dis. 2020 Dec 31.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Pyrimorph

    Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici.

  • Antibacterial agent ...

    Antibacterial agent 132 showed antimicrobial activity against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively.

  • Fluazinam

    Fluazinam is a pyridinamine fungicide with a broad spectrum of antifungal activity and had a strong inhibition effect on mycelial growth of S. sclerotiorum populations.?

Sign In Join Free