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Aminopeptidase-IN-1

CAS No. 374102-08-6

Aminopeptidase-IN-1( —— )

Catalog No. M35538 CAS No. 374102-08-6

Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Aminopeptidase-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.
  • Description
    Aminopeptidase-IN-1 (compound 16o) is a potent insulin-regulated aminopeptidase (IRAP) inhibitor with an Ki value of 7.7 μM. Aminopeptidase-IN-1 can be used tor research cognitive and memory impairments.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Aminopeptidase
  • Recptor
    Aminopeptidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    374102-08-6
  • Formula Weight
    356.33
  • Molecular Formula
    C18H16N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (280.64 mM; Ultrasonic )
  • SMILES
    CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1ccc(cc1)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mountford SJ, et al. Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase. J Med Chem. 2014 Feb 27;57(4):1368-77.?
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