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NLRP3-IN-11
CAS No. 2769040-91-5
NLRP3-IN-11( —— )
Catalog No. M35514 CAS No. 2769040-91-5
NLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 103 | In Stock |
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| 10MG | 150 | In Stock |
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| 25MG | 253 | In Stock |
|
| 50MG | 367 | In Stock |
|
| 100MG | 546 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNLRP3-IN-11
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NoteResearch use only, not for human use.
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Brief DescriptionNLRP3-IN-11 is an NLRP3 protein inhibitor with potential anti-inflammatory activity.NLRP3-IN-11 can be used in the study of atherosclerosis and parkinsonism.
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DescriptionNLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of <0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases.
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In VitroNLRP3-IN-11 has biological activity with an IC50 value of <0.3 μM in human PBMC NLRP3 assay.
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In Vivo——
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Synonyms——
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PathwayNF-κB
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TargetNOD
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RecptorNOD
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Research Area——
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Indication——
Chemical Information
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CAS Number2769040-91-5
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Formula Weight344.8
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Molecular FormulaC17H17ClN4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (362.53 mM; Ultrasonic )
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SMILESN(CC(C)(C)O)C=1C2=C(C(=NN1)C3=C(O)C=C(Cl)C=C3)C=CN=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1.
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