Cart
sales@molnova.com
UCB-5307
CAS No. 1515887-44-1
UCB-5307( —— )
Catalog No. M35511 CAS No. 1515887-44-1
UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 116 | In Stock |
|
| 10MG | 188 | In Stock |
|
| 25MG | 428 | In Stock |
|
| 50MG | 617 | In Stock |
|
| 100MG | 879 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1748 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUCB-5307
-
NoteResearch use only, not for human use.
-
Brief DescriptionUCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro.
-
DescriptionUCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetTNF
-
RecptorTNF
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1515887-44-1
-
Formula Weight343.42
-
Molecular FormulaC22H21N3O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (145.59 mM; Ultrasonic )
-
SMILESCc1ccc(C)c(Cn2c(nc3ccccc23)C(O)c2ccncc2)c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.?
molnova catalog
related products
-
GSK3145095
GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.
-
Bergamotine
Bergamotine can significantly reduce blood glucose and increase glucose tolerance and insulin sensitivity in diabetic mice.
-
Atibuclimab
Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.
