hCAIX-IN-5( —— )

Catalog No. M35467 CAS No. 2451479-57-3

hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	296	Get Quote
5MG	459	Get Quote
10MG	657	Get Quote
25MG	994	Get Quote
50MG	1371	Get Quote
100MG	1773	Get Quote
500MG	3537	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

hCAIX-IN-5
Note

Research use only, not for human use.
Brief Description

hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.
Description

hCAIX-IN-5 (compound 6b) is a potent and selective hCAIX inhibitor with KIs of >10000, >10000, 130.7, 829.1 nM for hCAI, hCAII, hCAIV, hCAIX, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

Carbonic Anhydrase
Recptor

Carbonic Anhydrase
Research Area

——
Indication

——

Chemical Information

CAS Number

2451479-57-3
Formula Weight

309.29
Molecular Formula

C18H12FNO3
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C(/C=C/C1=CC=C(F)C=C1)=O)C=2C=C3C(=CC2)OC(=O)C=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Swain B, et al. New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation. Bioorg Med Chem. 2020 Aug 1;28(15):115586.?

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