MAO-B-IN-17( —— )

Catalog No. M35461 CAS No. 2890188-81-3

MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) used in the study of central nervous system disorders, including Parkinson's.

Purity : >98% (HPLC)

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Biological Information

Product Name

MAO-B-IN-17
Note

Research use only, not for human use.
Brief Description

MAO-B-IN-17 is a selective and potent monoamine oxidase B (MAO-B) inhibitor (IC50: 5.08 μM) used in the study of central nervous system disorders, including Parkinson's.
Description

MAO-B-IN-17 is a selective monoamine oxidase B (MAO-B) inhibitor with the IC50 value of 5.08 μM. MAO-B-IN-17 can be used in Parkinson’s disease research.
In Vitro

MAO-B-IN-17 (Compound 4j) (10 μM, 24 h) shows no cytotoxic effect on human neuroblastoma cells.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

MAO
Recptor

MAO
Research Area

——
Indication

——

Chemical Information

CAS Number

2890188-81-3
Formula Weight

305.32
Molecular Formula

C17H17F2NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

FC=1C=C(F)C=C(C1)N2CC3=CC(OC)=C(OC)C=C3CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Med. Chem. Lett. 2022.

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