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MAO-B-IN-9
CAS No. 2416910-88-6
MAO-B-IN-9( —— )
Catalog No. M35454 CAS No. 2416910-88-6
MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 79 | Get Quote |
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| 5MG | 117 | Get Quote |
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| 10MG | 187 | Get Quote |
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| 25MG | 380 | Get Quote |
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| 50MG | 542 | Get Quote |
|
| 100MG | 770 | Get Quote |
|
| 500MG | 1512 | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMAO-B-IN-9
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NoteResearch use only, not for human use.
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Brief DescriptionMAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
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DescriptionMAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetBeta Amyloid
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RecptorBeta Amyloid | Monoamine Oxidase | Serotonin Transporter
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Research Area——
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Indication——
Chemical Information
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CAS Number2416910-88-6
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Formula Weight300.4
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Molecular FormulaC18H24N2O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO(C(NC1=CC=C(C(C)C)C=C1)=O)C2CCN(CC#C)CC2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Hoechst 34580
Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.Hoechst 34580 is a good candidate for treating Alzheimer’s disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner.
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β-Amyloid 1-28
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
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Amyloid beta-peptide...
Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells. The amino acid sequence of Aβ(25-35) peptide is NH2-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-COOH, where the first Gly represents the amino acid 25 and the last Met represents the amino acid 35 and it is also investigated in gel state for the first time.
