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Home - Products - MAPK/ERK Signaling - JNK - JNK-IN-11

JNK-IN-11

CAS No. 676594-38-0

JNK-IN-11( —— )

Catalog No. M35433 CAS No. 676594-38-0

JNK-IN-11 (compound 1) is a potent inhibitor of JNK, with IC50 values of 2.2 μM, 21.4 μM, and 1.8 μM for JNK1, JNK2, and JNK3, respectively, showing potential for Alzheimer's and Parkinson's disease research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    JNK-IN-11
  • Note
    Research use only, not for human use.
  • Brief Description
    JNK-IN-11 (compound 1) is a potent inhibitor of JNK, with IC50 values of 2.2 μM, 21.4 μM, and 1.8 μM for JNK1, JNK2, and JNK3, respectively, showing potential for Alzheimer's and Parkinson's disease research.
  • Description
    JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 μM for JNK1, JNK2, JNK3, respectively. JNK-IN-11 has the potential for the research of alzheimer and parkinson disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    JNK
  • Recptor
    JNK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    676594-38-0
  • Formula Weight
    281.35
  • Molecular Formula
    C12H11NO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(OC)C=1SC=CC1NC(=O)CC=2SC=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hom RK, et al. Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK. Bioorg Med Chem Lett. 2010 Dec 15;20(24):7303-7.?
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