Metapramine( —— )

Catalog No. M35401 CAS No. 21730-16-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Metapramine
Note

Research use only, not for human use.
Brief Description

Metapramine (19560 RP) is a novel psychostimulant, an N-methyl-D-aspartate receptor (NMDA) antagonist with antidepressant and anti-injury perception activity that promotes increased levels of acetylcholine in the striatum.
Description

Metapramine (19560 RP) is an antidepressant agent, belonging to the class of tricyclic compounds. Metapramine inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine. Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel.
In Vitro

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In Vivo

Metapramine (19560 RP) (0-20 mg/kg; i.p.) shows analgesic effects in mice.Animal Model:Male Swiss albino mice Dosage:0-20 mg/kg Administration:Intraperitoneal injection Result:Increased jump latency, threshold voltage, reduction in writhes, and tail flick latency in a dose-dependent manner.
Synonyms

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Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

Dehydrogenase
Research Area

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Indication

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1. M Bonierbale, et al. [Metapramine: antidepressant and psycho-stimulant]. Encephale. 1976;2(3):219-23.?

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