SCP1-IN-1

CAS No. 2764615-55-4

SCP1-IN-1( —— )

Catalog No. M35319 CAS No. 2764615-55-4

SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor of SCP1, promoting REST degradation and reducing transcriptional activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 116 In Stock
5MG 101 In Stock
10MG 163 In Stock
25MG 312 In Stock
50MG 461 In Stock
100MG 693 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SCP1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    SCP1-IN-1 (compound SH T-62) is a potent and selective covalent inhibitor of SCP1, promoting REST degradation and reducing transcriptional activity.
  • Description
    SCP1-IN-1 (compoundSH T-62) is a potent and selective covalent inhibitor against SCP1. SCP1-IN-1 promotes REST degradation and reduces transcriptional activity. A high level of REST protein drives the tumor growth in some glioblastoma cells. SCP1-IN-1 has the potential for the research of glioblastoma whose growth is driven by REST transcription activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2764615-55-4
  • Formula Weight
    520.5
  • Molecular Formula
    C20H19F3N2O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (192.12 mM; Ultrasonic )
  • SMILES
    FC(F)(F)Oc1ccc(cc1)S(=O)(=O)NCCOCCNC(=O)C1=Cc2ccccc2S1(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Medellin B, et al. Targeted Covalent Inhibition of Small CTD Phosphatase 1 to Promote the Degradation of the REST Transcription Factor in Human Cells. J Med Chem. 2022;65(1):507-519.?
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