Bifenthrin( —— )

Catalog No. M35278 CAS No. 82657-04-3

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Bifenthrin
Note

Research use only, not for human use.
Brief Description

Bifenthrin is a synthetic pyrethroid insecticide.Bifenthrin induces cell death in bovine mammary epithelial cells through ROS generation, disruption of calcium homeostasis, and alteration of the MAPK signaling cascade.Bifenthrin induces apoptosis by inducing cell-cycle arrest.
Description

Bifenthrin is a synthetic pyrethroid insecticide. Bifenthrin prolongs the opening time of Nav1.8 sodium channels, leading to membrane depolarization and conductance block in the insect nervous system, thereby disrupting neural function. Bifenthrin was effective in inhibiting A. gambiae (LD50=0.15 ng/mg) and C. quinquefasciatus (LD50=0.16 ng/mg). Bifenthrin has good lethality against susceptible and resistant mosquitoes and is very effective in inhibiting blood sucking and can be developed as a mosquito-removal netting material.
In Vitro

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In Vivo

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Synonyms

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Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis
Research Area

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Indication

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CAS Number

82657-04-3
Formula Weight

422.87
Molecular Formula

C23H22ClF3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (236.48 mM; Ultrasonic )
SMILES

C(=C(/C(F)(F)F)\Cl)\[C@H]1[C@@H](C(OCC2=C(C)C(=CC=C2)C3=CC=CC=C3)=O)C1(C)C
Chemical Name

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1. Hougard JM, et al. Bifenthrin: a useful pyrethroid insecticide for treatment of mosquito nets. J Med Entomol. 2002 May;39(3):526-33. ?

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