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Poly-D-lysine hydrobromide (MW 30000-70000)

CAS No. 27964-99-4

Poly-D-lysine hydrobromide (MW 30000-70000)( —— )

Catalog No. M35204 CAS No. 27964-99-4

Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is an oral peptide CaSR agonist that eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 46 In Stock
25MG 93 In Stock
50MG 145 In Stock
100MG 212 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Poly-D-lysine hydrobromide (MW 30000-70000)
  • Note
    Research use only, not for human use.
  • Brief Description
    Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is an oral peptide CaSR agonist that eliminates proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells.
  • Description
    Poly-D-lysine hydrobromide (MW 30000-70000) is a synthetic polymeric substrate and is one of the most widely used substrate in neural cell culture. Poly-D-lysine hydrobromide (MW 30000-70000) removes proteinase K-resistant PrP from prion-infected SN56 neuroblastoma cells without affecting PrPC.
  • In Vitro
    Poly-D-lysine is immunogenic in rabbits only when injected at low doses.The approximate concentration of Poly-D-lysine (PDL) needed to lower the amount of PrPres by 50% corresponds to ~0.8 μg/mL or 50 nM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    CaSR
  • Recptor
    CaSR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    27964-99-4
  • Formula Weight
  • Molecular Formula
    (C6H14N2O2)x.xHBr
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (Ultrasonic))
  • SMILES
    (C6H14N2O2)x.xHBr
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. HansVermeersch, et al. Immunogenicity of poly-D-lysine, a potential polymeric drug carrier. Journal of Controlled Release. Volume 32, Issue 3, 1 December 1994, Pages 225-229.
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