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B-Raf IN 2

CAS No. 2649372-20-1

B-Raf IN 2( —— )

Catalog No. M35194 CAS No. 2649372-20-1

B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.

Purity : >98% (HPLC)

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Size	Price / USD	Stock	Quantity
2MG	79	Get Quote
5MG	121	Get Quote
10MG	188	Get Quote
25MG	325	Get Quote
50MG	455	Get Quote
100MG	626	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

B-Raf IN 2
Note

Research use only, not for human use.
Brief Description

B-Raf IN 2, compound Ia, is a highly effective and specific inhibitor of BRAF. It exhibits significant potential for cancer research.
Description

B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. B-Raf IN 2 can be used for the research of cancer.
In Vitro

B-Raf IN 2 shows considerably less paradoxial activation of the MAPK signaling pathway while retaining high potency.
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

Raf
Recptor

Raf
Research Area

——
Indication

——

Chemical Information

CAS Number

2649372-20-1
Formula Weight

461.44
Molecular Formula

C20H17F2N5O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (216.71 mM; Ultrasonic )
SMILES

Cn1cnc2ccc(Oc3c(F)ccc(NS(=O)(=O)N4CC[C@@H](F)C4)c3C#N)cc2c1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dolente C, et, al. New methylquinazolinone derivatives. WO2021116055A1.

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