(E/Z)-E64FC26

CAS No. 2285446-67-3

(E/Z)-E64FC26( —— )

Catalog No. M35160 CAS No. 2285446-67-3

(E/Z)-E64FC26 is a potent protein disulfide isomerase (PDI) family inhibitor with potential antitumor activity and affinity for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6. (E/Z)-E64FC26 can be used for myeloma research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    (E/Z)-E64FC26
  • Note
    Research use only, not for human use.
  • Brief Description
    (E/Z)-E64FC26 is a potent protein disulfide isomerase (PDI) family inhibitor with potential antitumor activity and affinity for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6. (E/Z)-E64FC26 can be used for myeloma research.
  • Description
    (E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2285446-67-3
  • Formula Weight
    340.38
  • Molecular Formula
    C19H23F3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (293.79 mM; Ultrasonic )
  • SMILES
    FC(F)(F)C1=CC(=CCCCCCCCC)C=2C=C(O)C(O)=CC21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nathan G. Dolloff, et al. Indene derivatives and uses thereof. US20190062298A1.
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