PFB-FDGlu( —— )

Catalog No. M35123 CAS No. 209540-62-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

PFB-FDGlu
Note

Research use only, not for human use.
Brief Description

PFB-FDGlu is a lysosomal Glucocerebrosidase (GCase) substrate with cell-permeable specificity that is cleaved to produce fluorescein.
Description

PFB-FDGlu is a selective lysosomal Glucocerebrosidase (GCase) substrate, which is metabolised by GCase to yield fluorescein. PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis.
In Vitro

PFB-FDGlu is cell permeable and can be used with a flow cytometer to measure GCase activity in living cells on a single-cell basis.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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CAS Number

209540-62-5
Formula Weight

865.66
Molecular Formula

C39H32F5NO16
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (115.52 mM)
SMILES

O=C1OC2(C=3C1=CC(NC(=O)C4=C(F)C(F)=C(F)C(F)=C4F)=CC3)C=5C(OC=6C2=CC=C(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)C6)=CC(O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)=CC5
Chemical Name

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1. Hughes LP, et al. Flow Cytometry Measurement of Glucocerebrosidase Activity in Human Monocytes. Bio Protoc. 2020;10(7):e3572.?

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