TLR7 agonist 3
CAS No. 1229024-78-5
TLR7 agonist 3( —— )
Catalog No. M35052 CAS No. 1229024-78-5
TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 178 | Get Quote |
|
| 5MG | 275 | Get Quote |
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| 10MG | 455 | Get Quote |
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| 25MG | 725 | Get Quote |
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| 50MG | 1030 | Get Quote |
|
| 100MG | 1341 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameTLR7 agonist 3
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NoteResearch use only, not for human use.
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Brief DescriptionTLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.
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DescriptionTLR7 agonist 3 (Compound 2) is a potent agonist of toll-like receptor 7 (TLR7). TLR7 has an important role in immune activation processes and represents an emerging agent discovery target for the development of immunomodulators.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetTLR
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RecptorTLR
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Research Area——
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Indication——
Chemical Information
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CAS Number1229024-78-5
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Formula Weight312.41
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Molecular FormulaC18H24N4O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (320.09 mM; Ultrasonic ) Ethanol : ≥ 50 mg/mL (160.05 mM)
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SMILESOC(C)(C)CN1C(=NC=2C(=NC=3C=CC=CC3C21)N)CCCC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Loxoribine
Loxoribine is a guanosine analog. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) 7 agonist. It has anti-viral and anti-tumor activities.Loxoribine is a potent new immunostimulant with a relatively broad spectrum of immunobiological activities.
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GSK2245035
GSK2245035 is a highly potent, selective TLR7 agonist that selectively induces TFN-α in PBMC assays with pEC50 of 9.3, >2 logs selectivity over TNFα pEC50.
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M62812
TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects in PBMCs and HUVECs. Prolongs survival in a mouse septic shock model.
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