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DS44960156
CAS No. 2361327-08-2
DS44960156( —— )
Catalog No. M34971 CAS No. 2361327-08-2
DS44960156 is a novel selective inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 108 | Get Quote |
|
| 5MG | 163 | Get Quote |
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| 10MG | 250 | Get Quote |
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| 25MG | 419 | Get Quote |
|
| 50MG | 609 | Get Quote |
|
| 100MG | 858 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDS44960156
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NoteResearch use only, not for human use.
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Brief DescriptionDS44960156 is a novel selective inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.
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DescriptionDS44960156 is a selective Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor, with IC50 values of 1.6 μM and >30 μM for MTHFD2 and MTHFD1, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDHFR
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RecptorDHFR
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Research Area——
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Indication——
Chemical Information
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CAS Number2361327-08-2
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Formula Weight349.34
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Molecular FormulaC20H15NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (286.25 mM; Ultrasonic )
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SMILESOC(=O)c1ccc(cc1)C(=O)N1CCc2c(C1)c(=O)oc1ccccc21
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Junya Kawai, et al. Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold. ACS Med Chem Lett. 2019 May 24;10(6):893-898.?
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