Cart
sales@molnova.com
H-Leu-Leu-OMe HBr
CAS No. 16689-14-8
H-Leu-Leu-OMe HBr( —— )
Catalog No. M34891 CAS No. 16689-14-8
H-Leu-Leu-OMe HBr (L-Leucyl-L-Leucine methyl ester HBr) is a dipeptide condensation product of L-Leucine methyl ester, a peptide that is toxic to natural killer T-cells and possesses immunosuppressive activity that abrogates all natural killer (NK) cell functions in mixed lymphocyte populations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | Get Quote |
|
| 10MG | 61 | Get Quote |
|
| 25MG | 113 | Get Quote |
|
| 50MG | 170 | Get Quote |
|
| 100MG | 245 | Get Quote |
|
| 500MG | 597 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameH-Leu-Leu-OMe HBr
-
NoteResearch use only, not for human use.
-
Brief DescriptionH-Leu-Leu-OMe HBr (L-Leucyl-L-Leucine methyl ester HBr) is a dipeptide condensation product of L-Leucine methyl ester, a peptide that is toxic to natural killer T-cells and possesses immunosuppressive activity that abrogates all natural killer (NK) cell functions in mixed lymphocyte populations.
-
DescriptionL-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
RecptorEndogenous Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number16689-14-8
-
Formula Weight339.27
-
Molecular FormulaC13H27BrN2O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (368.44 mM; Ultrasonic )H2O : 100 mg/mL (294.75 mM; Ultrasonic)
-
SMILESBr.COC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Thiele DL, et, al. The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol. 1986 Feb 1;136(3):1038-48.?
molnova catalog
related products
-
1-Methyladenosine
1-Methyladenosine (M1A) belongs to the class of organic compounds known as purine nucleosides.
-
Palmitoleic acid
Palmitoleic acid is found to be associated with isovaleric acidemia which is an inborn error of metabolism.
-
Lignoceric Acid
Lignoceric Acid is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain.
