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DETA NONOate

CAS No. 146724-94-9

DETA NONOate( —— )

Catalog No. M34812 CAS No. 146724-94-9

DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    DETA NONOate
  • Note
    Research use only, not for human use.
  • Brief Description
    DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor with vasodilatory and antidepressant activity.DETA NONOate can be used to activate inward currents in neurons, which may accelerate the healing of MRSA-infected wounds.
  • Description
    DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor. DETA NONOate shows a slow release normal amounts of NO and long-acting.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Sprague-Dawley rats (Sixty-two, male, 200-250 g)Dosage:15 or 150 μg per rat Administration:i.c.v., once Result:Accelerated the nociception in a dose-dependent manner, and this acceleration was completely abolished by Methylene Blue (HY-14536).
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146724-94-9
  • Formula Weight
    163.18
  • Molecular Formula
    C4H13N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (306.41 mM; ultrasonic and adjust pH to 9 with H2O) DMSO : < 1 mg/mL (insoluble or slightly soluble)
  • SMILES
    CCNCC.CCN(CC)N(O)N=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Soichiro Sonoda, et al. Exogenous nitric oxide stimulates the odontogenic differentiation of rat dental pulp stem cells. Sci Rep. 2018 Feb 21;8(1):3419.?
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