Xanthohumol D

CAS No. 274675-25-1

Xanthohumol D( ——— )

Catalog No. M39017 CAS No. 274675-25-1

Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Xanthohumol D
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro.
  • Description
    Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    274675-25-1
  • Formula Weight
    370.401
  • Molecular Formula
    C21H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL (134.99 mM; ultraphonic; )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Choi Y, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 1;83(3):1048-52.?
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