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Izencitinib
CAS No. 2051918-33-1
Izencitinib( —— )
Catalog No. M34800 CAS No. 2051918-33-1
Izencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 206 | In Stock |
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| 5MG | 187 | In Stock |
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| 10MG | 297 | In Stock |
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| 25MG | 598 | In Stock |
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| 50MG | 918 | In Stock |
|
| 100MG | 1479 | In Stock |
|
| 200MG | 2027 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIzencitinib
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NoteResearch use only, not for human use.
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Brief DescriptionIzencitinib (JNJ-8398) is an orally active and gut-selective JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.
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DescriptionIzencitinib (TD-1473) is an orally active, non-selective and gut-restricted JAK inhibitor. Izencitinib (TD-1473) can be used in the study for ulcerative colitis.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetJAK
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RecptorJAK
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Research Area——
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Indication——
Chemical Information
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CAS Number2051918-33-1
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Formula Weight402.5
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Molecular FormulaC22H26N8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (124.22 mM; Ultrasonic )
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SMILESCc1cc(Nc2cc3ncccc3c(N[C@H]3C[C@@H]4CC[C@H](C3)N4CCC#N)n2)n[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kevin S Currie, et al. Small-molecule agents for the treatment of inflammatory bowel disease. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2034-2041.?
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