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Ecopipam
CAS No. 112108-01-7
Ecopipam( —— )
Catalog No. M34581 CAS No. 112108-01-7
Ecopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 107 | In Stock |
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| 10MG | 176 | In Stock |
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| 25MG | 353 | In Stock |
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| 50MG | 554 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEcopipam
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NoteResearch use only, not for human use.
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Brief DescriptionEcopipam (UNII-0X748O646K) is a potent, selective, and orally active antagonist of dopamine D1/D5 receptors, with Kis of 1.2 nM and 2.0 nM, respectively.
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DescriptionEcopipam (SCH 39166) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and α2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 μM, respectively). Ecopipam can be used for the research of schizophrenia and obesity.
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In Vitro——
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In VivoAnimal Model:Male young adult Long-Evans rats injected with Nicotine Dosage:0.003, 0.01, 0.03, 0.1, 0.3 mg/kg Administration:A single s.c. 20 min before Nicotine (0.1 mg/kg)Result:Dose-dependently reduced pressing on both active and inactive levers.
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Synonyms——
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorDopamine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number112108-01-7
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Formula Weight313.82
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Molecular FormulaC19H20ClNO
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1[C@@]2([C@@](C=3C(=CC(Cl)=C(O)C3)CC1)(C=4C(CC2)=CC=CC4)[H])[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wu WL, et, al. Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists. J Med Chem. 2005 Feb 10;48(3):680-93. ?
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