VRT-532

CAS No. 38214-71-0

VRT-532( —— )

Catalog No. M34468 CAS No. 38214-71-0

VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 141 In Stock
5MG 159 In Stock
10MG 238 In Stock
25MG 392 In Stock
50MG 520 In Stock
100MG 684 In Stock
200MG 905 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    VRT-532
  • Note
    Research use only, not for human use.
  • Brief Description
    VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.
  • Description
    VRT-532 (CFpot-532) is a potent is a potent CFTR modulator. VRT-532 enhances channel activity in G551D-CFTR and intrinsic ATPase activity of G551D-CFTR. VRT-532 has the potential for the research of cystic fibrosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    CFTR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38214-71-0
  • Formula Weight
    250.3
  • Molecular Formula
    C16H14N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=CC=C(O)C(=C1)C1=NNC(=C1)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pasyk S, et al. Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. Biochem J. 2009 Feb 15;418(1):185-90. ?
molnova catalog
related products
  • KM11060

    A potent corrector of the F508del-CFTR trafficking defect that partially restores F508del trafficking and increases maturation significantly in BHK cells.

  • Astressin 2B

    Potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist (IC50 values are 1.3 and > 500 nM for CRF2 and CRF1 respectively). Antagonizes CRF2-mediated inhibition of gastric emptying.

  • CFTR corrector 12

    CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3, and can be used to study cystic fibrosis.