VRT-532

CAS No. 38214-71-0

VRT-532( —— )

Catalog No. M34468 CAS No. 38214-71-0

VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 240 Get Quote
5MG 376 Get Quote
10MG 566 Get Quote
25MG 908 Get Quote
50MG 1224 Get Quote
100MG 1575 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    VRT-532
  • Note
    Research use only, not for human use.
  • Brief Description
    VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects.
  • Description
    VRT-532 (CFpot-532) is a potent is a potent CFTR modulator. VRT-532 enhances channel activity in G551D-CFTR and intrinsic ATPase activity of G551D-CFTR. VRT-532 has the potential for the research of cystic fibrosis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    CFTR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    38214-71-0
  • Formula Weight
    250.3
  • Molecular Formula
    C16H14N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1=CC=C(O)C(=C1)C1=NNC(=C1)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pasyk S, et al. Direct interaction of a small-molecule modulator with G551D-CFTR, a cystic fibrosis-causing mutation associated with severe disease. Biochem J. 2009 Feb 15;418(1):185-90. ?
molnova catalog
related products
  • SRI-37240

    SRI-37240 is a potent inhibitor of premature termination codons (PTCs) with read-across activity that induces a prolonged pause at the termination codon and inhibits PTCs associated with cystic fibrosis.

  • BPO-27 racemate

    BPO-27 is a potent, metabolically stable CFTR inhibitor (IC50= 8 nM).

  • CFTR corrector 9

    CFTR Corrector 9, a cystic fibrosis transmembrane conductance regulator (CFTR) modulator, is employed in the research of cystic fibrosis (CF) and related CFTR-associated disorders .