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DNDS

CAS No. 3709-43-1

DNDS( DNS )

Catalog No. M27251 CAS No. 3709-43-1

DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DNDS
  • Note
    Research use only, not for human use.
  • Brief Description
    DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
  • Description
    DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DNS
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    mGluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3709-43-1
  • Formula Weight
    474.32
  • Molecular Formula
    C14H8N2Na2O10S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [Na+].[Na+].[O-][N+](=O)c1ccc(\C=C\c2ccc(cc2S([O-])(=O)=O)[N+]([O-])=O)c(c1)S([O-])(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, Walker AG, Melancon BJ, Wood MR, Lindsley CW, Conn PJ, Xiang Z, Hopkins CR, Niswender CM. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. doi: 10.1021/cn500153z. Epub 2014 Oct 9. PubMed PMID: 25225882; PubMed Central PMCID: PMC4306484.
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