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DNDS
CAS No. 3709-43-1
DNDS( DNS )
Catalog No. M27251 CAS No. 3709-43-1
DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 27 | In Stock |
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Biological Information
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Product NameDNDS
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NoteResearch use only, not for human use.
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Brief DescriptionDNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
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DescriptionDNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).
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In Vitro——
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In Vivo——
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SynonymsDNS
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PathwayApoptosis
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TargetCFTR
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RecptormGluR
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Research Area——
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Indication——
Chemical Information
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CAS Number3709-43-1
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Formula Weight474.32
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Molecular FormulaC14H8N2Na2O10S2
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Purity>98% (HPLC)
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Solubility——
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SMILES[Na+].[Na+].[O-][N+](=O)c1ccc(\C=C\c2ccc(cc2S([O-])(=O)=O)[N+]([O-])=O)c(c1)S([O-])(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jalan-Sakrikar N, Field JR, Klar R, Mattmann ME, Gregory KJ, Zamorano R, Engers DW, Bollinger SR, Weaver CD, Days EL, Lewis LM, Utley TJ, Hurtado M, Rigault D, Acher F, Walker AG, Melancon BJ, Wood MR, Lindsley CW, Conn PJ, Xiang Z, Hopkins CR, Niswender CM. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. doi: 10.1021/cn500153z. Epub 2014 Oct 9. PubMed PMID: 25225882; PubMed Central PMCID: PMC4306484.
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