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VX661

CAS No. 1152311-62-0

VX661( Tezacaftor )

Catalog No. M10537 CAS No. 1152311-62-0

VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 68 In Stock
10MG 113 In Stock
25MG 201 In Stock
50MG 324 In Stock
100MG 478 In Stock
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Biological Information

  • Product Name
    VX661
  • Note
    Research use only, not for human use.
  • Brief Description
    VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
  • Description
    VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Tezacaftor
  • Pathway
    Apoptosis
  • Target
    CFTR
  • Recptor
    VFTR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1152311-62-0
  • Formula Weight
    520.5
  • Molecular Formula
    C26H27F3N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 100 mg/mL (192.12 mM)
  • SMILES
    O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=CC5=C(N(C[C@@H](O)CO)C(C(C)(C)CO)=C5)C=C4F
  • Chemical Name
    (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pettit RS, Fellner C. P T. 2014 Jul;39(7):500-12. Veit G, et al. Sci Transl Med. 2014 Jul 23;6(246):246ra97.
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