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VX661
CAS No. 1152311-62-0
VX661( Tezacaftor )
Catalog No. M10537 CAS No. 1152311-62-0
VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 86 | In Stock |
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| 2MG | 46 | In Stock |
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| 5MG | 71 | In Stock |
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| 10MG | 119 | In Stock |
|
| 25MG | 212 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 494 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVX661
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NoteResearch use only, not for human use.
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Brief DescriptionVX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
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DescriptionVX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
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In Vitro——
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In Vivo——
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SynonymsTezacaftor
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PathwayApoptosis
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TargetCFTR
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RecptorVFTR
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1152311-62-0
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Formula Weight520.5
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Molecular FormulaC26H27F3N2O6
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL (192.12 mM)
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SMILESO=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=CC5=C(N(C[C@@H](O)CO)C(C(C)(C)CO)=C5)C=C4F
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Chemical Name(R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pettit RS, Fellner C. P T. 2014 Jul;39(7):500-12. Veit G, et al. Sci Transl Med. 2014 Jul 23;6(246):246ra97.
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