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VX661

CAS No. 1152311-62-0

VX661( Tezacaftor )

Catalog No. M10537 CAS No. 1152311-62-0

VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	86	In Stock
2MG	46	In Stock
5MG	71	In Stock
10MG	119	In Stock
25MG	212	In Stock
50MG	335	In Stock
100MG	494	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

VX661
Note

Research use only, not for human use.
Brief Description

VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
Description

VX-661 is a second F508del CFTR corrector and is believed to help CFTR protein reach the cell surface. Phase 2.
In Vitro

——
In Vivo

——
Synonyms

Tezacaftor
Pathway

Apoptosis
Target

CFTR
Recptor

VFTR
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

1152311-62-0
Formula Weight

520.5
Molecular Formula

C26H27F3N2O6
Purity

>98% (HPLC)
Solubility

DMSO: 100 mg/mL (192.12 mM)
SMILES

O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=CC5=C(N(C[C@@H](O)CO)C(C(C)(C)CO)=C5)C=C4F
Chemical Name

(R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pettit RS, Fellner C. P T. 2014 Jul;39(7):500-12. Veit G, et al. Sci Transl Med. 2014 Jul 23;6(246):246ra97.

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