Cart
sales@molnova.com
Home - Products - Metabolic Enzyme/Protease - P450 - LY 43578

LY 43578

CAS No. 26766-35-8

LY 43578( —— )

Catalog No. M34324 CAS No. 26766-35-8

LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 46 In Stock
10MG 73 In Stock
25MG 117 In Stock
50MG 172 In Stock
100MG 250 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    LY 43578
  • Note
    Research use only, not for human use.
  • Brief Description
    LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.
  • Description
    LY43578 is anorally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    P450
  • Recptor
    P450 | Aromatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    26766-35-8
  • Formula Weight
    331.2
  • Molecular Formula
    C17H12Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(O)(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)C=3C=NC=NC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Toddalolactone

    anti-inflammatory and analgesic.

  • Alpha-Amyrin

    Alpha-Amyrin is an inhibitor of trypsin and chymotrypsin with antineoplastic effects. alpha-Amyrin can be used in studies about acting as a hepatomodulatory.

  • Epimedin A1

    Epimedin A1(Hexandraside F) is a flavonoid extracted from Herba Epimedii which is one of commonly used Chinese medicines.

Sign In Join Free