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ISAM-140
CAS No. 932191-62-3
ISAM-140( —— )
Catalog No. M34288 CAS No. 932191-62-3
ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 81 | Get Quote |
|
| 5MG | 121 | Get Quote |
|
| 10MG | 175 | Get Quote |
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| 25MG | 273 | Get Quote |
|
| 50MG | 413 | Get Quote |
|
| 100MG | 572 | Get Quote |
|
| 500MG | 1125 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameISAM-140
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NoteResearch use only, not for human use.
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Brief DescriptionISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.
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DescriptionISAM-140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM.
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In VitroISAM-140 (22b) (0.1-100 μM) inhibits NECA (5'-N-ethylcarboxamido adenosine)-stimulated cAMP accumulation.ISAM-140 shows a KB value of 27.00 nM.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAdenosine Receptor
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RecptorAdenosine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number932191-62-3
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Formula Weight337.37
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Molecular FormulaC19H19N3O3
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Purity>98% (HPLC)
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Solubility——
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SMILESC(OC(C)C)(=O)C=1C(N2C(NC=3C2=CC=CC3)=NC1C)C4=CC=CO4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. El Maatougui A, et al. Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes. J Med Chem. 2016 Mar 10;59(5):1967-83. ?
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