Cart
sales@molnova.com
BMS641
CAS No. 369364-50-1
BMS641( —— )
Catalog No. M34187 CAS No. 369364-50-1
BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 249 | In Stock |
|
| 5MG | 226 | In Stock |
|
| 10MG | 377 | In Stock |
|
| 25MG | 730 | In Stock |
|
| 50MG | 1014 | In Stock |
|
| 100MG | 1376 | In Stock |
|
| 200MG | 1851 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBMS641
-
NoteResearch use only, not for human use.
-
Brief DescriptionBMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
-
DescriptionBMS641 (BMS-209641) is a selective RARβ agonist. BMS641 has a higher affinity for RARβ (Kd, 2.5 nM) that is 100 times higher than that for RARα (Kd, 225 nM) or RARγ (Kd, 223 nM).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetRetinoid Receptor
-
RecptorRetinoid Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number369364-50-1
-
Formula Weight414.92
-
Molecular FormulaC27H23ClO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 8.33 mg/mL (20.08 mM; Ultrasonic )
-
SMILESCC1(C)C=2C(C(=CC1)C3=CC=CC=C3)=CC(/C=C/C4=C(Cl)C=C(C(O)=O)C=C4)=CC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Germain P, et al. Rational design of RAR-selective ligands revealed by RARbeta crystal stucture. EMBO Rep. 2004;5(9):877-882. ?
molnova catalog
related products
-
LG-100064
LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)LG-100064 shows no effect on RARα/β/γ (EC50, >10000 nM).LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ.
-
CD 1530
CD 1530 is a selective and potent RARγ agonist (Kd:150 nM) with potential anticancer activity, shows insecticidal activity against Cryptobacterium hidradii nematodes, and can be used to study oral carcinogenesis.
-
Tamibarotene
Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.
