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BMS641

CAS No. 369364-50-1

BMS641( —— )

Catalog No. M34187 CAS No. 369364-50-1

BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	249	In Stock
5MG	226	In Stock
10MG	377	In Stock
25MG	730	In Stock
50MG	1014	In Stock
100MG	1376	In Stock
200MG	1851	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BMS641
Note

Research use only, not for human use.
Brief Description

BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
Description

BMS641 (BMS-209641) is a selective RARβ agonist. BMS641 has a higher affinity for RARβ (Kd, 2.5 nM) that is 100 times higher than that for RARα (Kd, 225 nM) or RARγ (Kd, 223 nM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Retinoid Receptor
Recptor

Retinoid Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

369364-50-1
Formula Weight

414.92
Molecular Formula

C27H23ClO2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 8.33 mg/mL (20.08 mM; Ultrasonic )
SMILES

CC1(C)C=2C(C(=CC1)C3=CC=CC=C3)=CC(/C=C/C4=C(Cl)C=C(C(O)=O)C=C4)=CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Germain P, et al. Rational design of RAR-selective ligands revealed by RARbeta crystal stucture. EMBO Rep. 2004;5(9):877-882. ?

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