CAY10444
CAS No. 298186-80-8
CAY10444( —— )
Catalog No. M33970 CAS No. 298186-80-8
CAY10444 is an S1P3 specific antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 140 | In Stock |
|
| 50MG | 230 | In Stock |
|
| 100MG | 384 | In Stock |
|
| 200MG | 522 | In Stock |
|
| 500MG | 821 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCAY10444
-
NoteResearch use only, not for human use.
-
Brief DescriptionCAY10444 is an S1P3 specific antagonist.
-
DescriptionCAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors.
-
In VitroBML-241 inhibits increases in intracellular Ca2+ concentration via P2 receptor or α1A-adrenoceptor stimulation and α1A-adrenoceptor-mediated contraction of rat mesenteric artery, while it does not affect S1P3-mediated decrease of Forskolin-induced cyclic AMP accumulation.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number298186-80-8
-
Formula Weight287.46
-
Molecular FormulaC15H29NO2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 41.67 mg/mL (144.96 mM; Ultrasonic (<80°C)
-
SMILESCCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
Cy3 NHS ester
Cy3 NHS ester is a fluorescent dye used to label amino groups in proteins, peptides, antibodies, and oligonucleotides. The excitation/emission (Ex/Em) values ??of Cy3 NHS ester are 550 nm/570 nm.
-
Leritrelvir
Leritrelvir (RAY1216) is a potent orally active inhibitor of the SARS-CoV-2 main protease, exhibiting a slow-tight binding mechanism with an inhibition constant (Ki) of 8.6 nM .
-
Galanin (1-13)-Subst...
Galantide, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in the rat hypothalamus. Galantide dose dependently (IC50=1.0 nM) antagonizes the galanin-mediated inhibition of the glucose-induced insulin secretion from mouse pancreatic islets. Galantide appears to bind to a single population of SP receptors (KD~40 nM).
Cart
sales@molnova.com