SCH 221510( —— )

Catalog No. M33925 CAS No. 322473-89-2

SCH 221510 is an orally available, selective and potent NOP agonist with an EC50 of 12 nM and a Ki of 0.3 nM.SCH 221510 has anxiolytic activity and can be used to study neurological disorders.

Purity : >98% (HPLC)

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Biological Information

Product Name

SCH 221510
Note

Research use only, not for human use.
Brief Description

SCH 221510 is an orally available, selective and potent NOP agonist with an EC50 of 12 nM and a Ki of 0.3 nM.SCH 221510 has anxiolytic activity and can be used to study neurological disorders.
Description

SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC50 of 12 nM and Ki of 0.3 nM. SCH 221510 shows an anxiolytic-like effect.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Endocrinology/Hormones
Target

Opioid Receptor
Recptor

Opioid Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

322473-89-2
Formula Weight

397.55
Molecular Formula

C28H31NO
Purity

>98% (HPLC)
Solubility

——
SMILES

C(N1[C@@]2(C[C@@](O)(C[C@]1(CC2)[H])C3=CC=CC=C3)[H])(C4=C(C)C=CC=C4)C5=C(C)C=CC=C5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Varty GB, et al. The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510). J Pharmacol Exp Ther. 2008 Aug;326(2):672-82.?

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