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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - GW 542573X

GW 542573X

CAS No. 660846-41-3

GW 542573X( —— )

Catalog No. M33861 CAS No. 660846-41-3

GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 73 In Stock
10MG 126 In Stock
25MG 264 In Stock
50MG 431 In Stock
100MG 586 In Stock
200MG 788 In Stock
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Biological Information

  • Product Name
    GW 542573X
  • Note
    Research use only, not for human use.
  • Brief Description
    GW 542573X is a potent and selective small molecule Ca2+-activated K+ 2 (SK2) channel activator.
  • Description
    GW542573X is a potent and selective Ca2+-activated K+ 2 (SK2) channels activator. GW542573X induces the Ca2+-response curve of hSK1 that left-shifted from an EC50 (Ca2+) value of 410 nM to 240 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    Potassium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    660846-41-3
  • Formula Weight
    364.44
  • Molecular Formula
    C19H28N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (342.99 mM; Ultrasonic )
  • SMILES
    N(C(OCC1CCN(C(OC(C)(C)C)=O)CC1)=O)C2=C(OC)C=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hougaard C, et, al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol Pharmacol. 2009 Sep;76(3):569-78.?
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