(E)-FeCP-oxindole( —— )

Catalog No. M33847 CAS No. 884338-18-5

(E)-FeCP-oxindole is an inhibitor of VEGFR2 with IC50 of 214 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	219	Get Quote
25MG	357	Get Quote
50MG	507	Get Quote
100MG	675	Get Quote
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Biological Information

Product Name

(E)-FeCP-oxindole
Note

Research use only, not for human use.
Brief Description

(E)-FeCP-oxindole is an inhibitor of VEGFR2 with IC50 of 214 nM.
Description

(Z)-FeCP-oxindole is a selective human vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with an IC50 value of 200 nM. (Z)-FeCP-oxindole can significantly inhibit VEGFR1 and PDGFRa or b at 10 μM. (Z)-FeCP-oxindole has some anticancer activity, acting on B16 murine melanoma lines with IC50 less than 1 μM.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Angiogenesis
Target

VEGFR
Recptor

VEGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

884338-18-5
Formula Weight

329.17
Molecular Formula

C19H15FeNO
Purity

>98% (HPLC)
Solubility

——
SMILES

C(\[C-]12[Fe+2]3456789([CH]1=[CH]3[CH]4=[CH]52)[CH-]%10[CH]6=[CH]7[CH]8=[CH]9%10)=C/%11\C=%12C(NC%11=O)=CC=CC%12
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. John Spencer, et al. Synthesis and evaluation of metallocene containing methylidene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors. Metallomics. 2011 Jun;3(6):600-8.?

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