Cart
sales@molnova.com
Vesamicol hydrochloride
CAS No. 120447-62-3
Vesamicol hydrochloride( —— )
Catalog No. M33820 CAS No. 120447-62-3
Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 31 | In Stock |
|
| 5MG | 49 | In Stock |
|
| 10MG | 75 | In Stock |
|
| 25MG | 150 | In Stock |
|
| 50MG | 219 | In Stock |
|
| 100MG | 323 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVesamicol hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionVesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
-
Description(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a potent vesicular acetylcholine transport inhibitor with a Ki of 2 nM. (±)-Vesamicol hydrochloride also displays high affinity for σ1 and σ2 receptors with Kis of 26 nM and 34 nM, respectively.
-
In Vitro——
-
In VivoAnimal Model:Male Wistar rats (120-300 g)Dosage:3 mg/kg Administration:Intraperitoneal injection; once Result:The levels of cytosolic acetylcholine (ACh) increased in all regions of the brain, while those of vesicular ACh decreased in all regions except for the striatum.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetAChR
-
RecptorAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number120447-62-3
-
Formula Weight295.85
-
Molecular FormulaC17H26ClNO
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 20.83 mg/mL (70.41 mM; Ultrasonic (<60°C)
-
SMILESCl.OC1CCCCC1N1CCC(CC1)C1=CC=CC=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. S M Efange, et al. N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J Med Chem. 1997 Nov 21;40(24):3905-14.?
molnova catalog
related products
-
ICL-CCIC-0019
ICL-CCIC-0019 is an inhibitor of choline kinase alpha (ChoKα). ICL-CCIC-0019 induces G1 arrest, endoplasmic reticulum stress, and apoptosis of cancer cell lines.
-
Thiacloprid
Thiacloprid, a chloronicotinyl insecticide, acts as a selective agonist at insect nAChRs. The IC50 values are 2.7 and 860 nM for Drosophilan AChRs and M10 mouse fibroblast cells expressing α4β2 subunit-containing nAChRs, respectively.
-
GSK233705
GSK233705 (Darotropium bromide) is a muscarinic receptor antagonist used in conjunction with the prevention and treatment of chronic obstructive pulmonary disease (COPD) and asthma in humans.
