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PTP Inhibitor IV
CAS No. 329317-98-8
PTP Inhibitor IV( —— )
Catalog No. M33787 CAS No. 329317-98-8
PTP Inhibitor IV is an effective protein tyrosine phosphatase (PTP) inhibitor, which can selectively inhibit DUSP14 phosphatase activity (IC50.5.21μm).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
|
| 5MG | 36 | In Stock |
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| 10MG | 56 | In Stock |
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| 25MG | 129 | In Stock |
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| 50MG | 205 | In Stock |
|
| 100MG | 330 | In Stock |
|
| 200MG | 456 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePTP Inhibitor IV
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NoteResearch use only, not for human use.
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Brief DescriptionPTP Inhibitor IV is an effective protein tyrosine phosphatase (PTP) inhibitor, which can selectively inhibit DUSP14 phosphatase activity (IC50.5.21μm).
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DescriptionPTP Inhibitor IV is a protein tyrosine phosphatase (PTP) inhibitor that competitively inhibits DUSP14 phosphatase activity with an 50 of 5.21 μM. PTP Inhibitor IV inhibits SHP-2, PTP1B, PTP-ε, PTP Meg-2, PTP-σ, PTP-β, and PTP-μ with 50s of 1.8 μM, 2.5 μM, 8.4 μM, 13 μM, 20 μM, 6.4 μM, and 6.7 μM, respectively.
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In VitroWestern Blot Analysis Cell Line:HEK 293 cells Concentration:0, 10 μM, 50 μM, or 100 μM Incubation Time:3 hours Result: Effectively penetrated the cells and inhibited DUSP14 activity.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorPhosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number329317-98-8
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Formula Weight608.62
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Molecular FormulaC26H26F6N2O4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (410.77 mM; Ultrasonic )
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SMILESC(C)(C)(C1=CC=C(C(C)(C)C2=CC=C(NS(C(F)(F)F)(=O)=O)C=C2)C=C1)C3=CC=C(NS(C(F)(F)F)(=O)=O)C=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jae Eun Park, et al. PTP inhibitor IV protects JNK kinase activity by inhibiting dual-specificity phosphatase 14 (DUSP14). Biochem Biophys Res Commun. 2009 Oct 2;387(4):795-9. ?
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