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Home - Products - Metabolic Enzyme/Protease - Retinoid Receptor - BMS 753

BMS 753

CAS No. 215307-86-1

BMS 753( —— )

Catalog No. M33783 CAS No. 215307-86-1

BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 55 In Stock
5MG 55 In Stock
10MG 92 In Stock
25MG 212 In Stock
50MG 333 In Stock
100MG 462 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    BMS 753
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).
  • Description
    BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.
  • In Vitro
    BMS 753 results in low levels of RARβ transcripts in WT cells, RARγ-/-, but not activates in RARa-/- cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Retinoid Receptor
  • Recptor
    Retinoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    215307-86-1
  • Formula Weight
    351.4
  • Molecular Formula
    C21H21NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (142.29 mM; Ultrasonic )
  • SMILES
    CC1(C)C(=O)C(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. M Géhin, et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem Biol. 1999 Aug;6(8):519-29.?
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